Mauro Elias Mesko, Brian Hutton, [...], and Tatiana Pereira-Cenci
Reference
(Ref ID): PMC5237268
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Document structure and format:
I. Introduction
This research paper titled "Therapies for bruxism: a systematic review and network meta-analysis (protocol)" aims to explore the best treatment options for adults with bruxism, a sleep disorder characterized by grinding and clenching of the teeth. The paper addresses the lack of definitive answers regarding the most effective treatments for the different manifestations of bruxism.
II. Methodology
The study follows a systematic review and network meta-analysis methodology. Comprehensive searches will be conducted using various databases to identify relevant studies that meet the eligibility criteria. Data extraction will be performed using a specially designed sheet, and the risk of bias of included studies will be assessed. The overall strength of evidence will be summarized using the GRADE approach. Statistical analyses including pairwise meta-analyses and Bayesian network meta-analysis will be employed to compare the benefits of different therapies.
III. Results
The key findings of this research are yet to be determined as the study protocol is described in this paper. The results of the systematic review and network meta-analysis will provide insights into the best treatment options for adult bruxists.
IV. Discussion
The authors will analyze and interpret the results in relation to the research question and objectives. They will discuss the implications and significance of the study's findings for both patients and researchers. Additionally, any limitations or areas for further research will be addressed.
V. Conclusion
In conclusion, this research paper provides a protocol for a systematic review and network meta-analysis that aims to identify the best therapies for bruxism in adults. The findings of this study have the potential to offer recommendations for the clinical management of bruxism and guide future research.
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